Arsenal v Man City (16:00 GMT)
Manchester City have always been cautious when they have gone to the Emirates Stadium under Roberto Mancini - it has been a case of him saying: "I'm an Italian manager, I'm not going to get beaten."
Arsenal did beat City at the end of last season - on Easter Sunday to leave Manchester United eight points clear at the top - and the Gunners also gave the champions a very good game when they drew at the Etihad Stadium in September.
So I am not sure how City will approach this one. United are seven points clear and I just wonder whether Mancini's thinking might change depending on how their rivals get on against Liverpool earlier in the day.
If United lose or draw, then perhaps Mancini will go for it - although we have to remember that he is Italian!
From Arsenal's point of view, it will be interesting to see whether Arsene Wenger plays Theo Walcott down the middle. That will be the big call for him.
City are without Yaya Toure, who is on Africa Cup of Nations duty with Ivory Coast, and you cannot overstate how much of a loss he is to their midfield.
I know he has not been quite the same player he was last season, but they still miss him badly because on his day he drives them forward.
Lawro's prediction: 1-1