Man Utd v Arsenal (12:45 GMT)
Both these teams conceded five goals in the Capital One Cup in midweek but I definitely don't expect to see as many goals flying in at Old Trafford as there were in this fixture last season, when I was there to watch Manchester United win 8-2.
United's 5-4 defeat by Chelsea on Wednesday was a mad game but Sir Alex Ferguson fielded a really inexperienced centre-back pairing in Michael Keane and Scott Wootton, who will still have got more out of that game than some of the more experienced Blues players.
The team Ferguson picks on Saturday will not resemble that line-up and I think they will just be too strong for Arsenal.
It is a really good time to play the Gunners, who fought back to beat Reading 7-5 on Tuesday but have been struggling to find their form in the last couple of weeks. I don't think Arsene Wenger's side have got enough forward power to trouble United's defence.
United are a little weak at the back at the moment but Chris Smalling could be available on Saturday and, slowly but surely, as players like Phil Jones and Nemanja Vidic come back from injury, they will improve defensively.
Arsenal could struggle at the other end too. United seem to be able to create chances at will and have a real embarrassment of riches up front. Ferguson's problem is who to leave out.
The spotlight will be on United's former Arsenal striker Robin van Persie but it is a little difficult the first time you play against your old team because I think you try a bit too hard to prove what a good player you are.
Even so, if it is not Van Persie making the difference up front, it could be Javier Hernandez, Wayne Rooney, Danny Welbeck or Antonio Valencia. Take your pick.
That was one of the impressive things about the way United beat Chelsea in the league last weekend. They picked Antonio Valencia and Ashley Young up front and completely flipped Chelsea's attacking tactics back on to them.
Will Ferguson carry on using wingers this week or revert to his midfield diamond? If I were him, I would be reluctant to drop Valencia, who showed us again what a good player he is.
Whatever Ferguson's formation, after seeing United go to Chelsea and win last weekend, I would be very surprised if they slip up in a game like this.
Prediction: 2-0