Certainly should play pub teams at Emirates with this line up & drop the need for a DM. At home against the pub teams the ball spends 80% of its time in their half, this is where you need your players.
As I think Sanch has better work rate, I'd play Rambo on his side of midfield allowing him a bit more freedom to make his forward runs. So its a simple swap of Rambo & Jack for me.