I think you would need to tie a piece of rope between the pair of them given Ramsey's instincts and the fact he's suddenly high on goals again with the latest hat trick........and even then Ramsey would drag Wilshere out of position and expose them both.
My worry is that if you play a 2 man midfield against Spurs' 3 with Dembele in there, then they will simply boss the game in midfield like they did for spells against Man United.
If they boss the game in midfield then they will continually supply Kane.....and to my mind even better than his actual finishing, Kane's greatest attribute is the frequency of opportunities he gets for himself, a little like Andy Cole at United used to.
I can't remember which podcast I heard it on....but they were suggesting that the latest stats show it is frequency of chances a team should focus on rather than the actual quality of them. Oh it was the Arsenal vision podcast and unsurprisingly they were talking about Cavani, who is an interesting subject matter regarding quality of finishing and frequency of chances.